Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 8/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | AHR | P35869 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.67 |
| ▸ | CLK4 | Q9HAZ1 | 8/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.60 |
| ▸ | LMNA | P02545 | 7/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.56 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4008515 | 0.94 | MAPT (0.80) | MAPK1MAPTAHRHTTPI4KB | |
| SCHEMBL4007596 | 0.94 | MAPK1 (0.64) | MAPK1MAPTAHRHTTPI4KB | |
| SCHEMBL4013714 | 0.94 | MAPK1 (0.64) | MAPK1MAPTAHRHTTPI4KB | |
| SCHEMBL4009789 | 0.91 | MAPK1 (0.61) | MAPK1MAPTAHRHTTPI4KB | |
| SCHEMBL14026142 | 0.89 | MAPK1 (0.72) | MAPK1MAPTAHRHTTPI4KB | |
| SCHEMBL4885395 | 0.86 | MAPK1 (0.64) | MAPK1MAPTAHRHTTPI4KB | |
| SCHEMBL4886107 | 0.85 | MAPT (0.67) | MAPK1MAPTAHRHTTPI4KB | |
| SCHEMBL4013688 | 0.85 | MAPK1 (0.67) | MAPK1MAPTAHRHTTPI4KB | |
| SCHEMBL4789541 | 0.84 | MAPT (0.66) | MAPK1MAPTAHRHTTPI4KB | |
| SCHEMBL4007243 | 0.84 | CYP1A2 (0.67) | MAPK1MAPTAHRHTTPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844004-B1 | QUINAZOLINE DERIVATES AS ANTIVIRAL AGENTS | ARROW THERAPEUTICS LTD (GB) | 2009-06-24 | — | — | EP | disclosed |
| US-20080114008-A1 | Quinazoline Derivatives as Antiviral Agents | ARROW THERAPEUTICS LIMITED (GB) | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080114008-A1 | Quinazoline Derivatives as Antiviral Agents | IFNAR1, C5, EIF2AK2 | MAPK1 3003/4885MAPT 4840/4885AHR 850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.