Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 13/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 13/20 | 0.67 |
| ▸ | CLK4 | Q9HAZ1 | 12/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.67 |
| ▸ | USP2 | O75604 | 9/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.66 |
| ▸ | AHR | P35869 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | EGFR | P00533 | 2/20 | 0.57 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4007548 | 0.96 | MAPK1 (0.63) | CYP1A2CYP3A4CLK4CYP2D6USP2 | |
| SCHEMBL4010987 | 0.95 | ALDH1A1 (0.64) | CYP1A2CYP3A4CLK4CYP2D6USP2 | |
| SCHEMBL4013832 | 0.92 | MAPK1 (0.60) | CYP1A2CYP3A4CLK4CYP2D6USP2 | |
| SCHEMBL4008515 | 0.89 | MAPT (0.80) | CYP1A2CYP3A4CLK4CYP2D6USP2 | |
| SCHEMBL5103599 | 0.87 | MAPT (0.62) | CYP1A2CYP3A4CLK4CYP2D6USP2 | |
| SCHEMBL4791053 | 0.87 | MAPT (0.61) | CYP1A2CYP3A4CLK4CYP2D6USP2 | |
| SCHEMBL4759642 | 0.86 | SRC (0.60) | CYP1A2CYP3A4CLK4CYP2D6USP2 | |
| SCHEMBL4007152 | 0.84 | MAPK1 (0.72) | CYP1A2CYP3A4CLK4CYP2D6USP2 | |
| SCHEMBL14026142 | 0.84 | MAPK1 (0.72) | CYP1A2CYP3A4CLK4CYP2D6USP2 | |
| SCHEMBL4011562 | 0.84 | PI4KB (0.62) | CYP1A2CYP3A4CLK4CYP2D6USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844004-B1 | QUINAZOLINE DERIVATES AS ANTIVIRAL AGENTS | ARROW THERAPEUTICS LTD (GB) | 2009-06-24 | — | — | EP | disclosed |
| US-20080114008-A1 | Quinazoline Derivatives as Antiviral Agents | ARROW THERAPEUTICS LIMITED (GB) | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080114008-A1 | Quinazoline Derivatives as Antiviral Agents | IFNAR1, C5, EIF2AK2 | CYP1A2 313/4885CYP3A4 122/4885CLK4 1443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.