Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.45 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.43 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | IDH2 | P48735 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4008586 | 0.90 | TRPV1 (0.47) | GPR35TRPV1SERPINE1NTRK1IGF2BP2 | |
| SCHEMBL1239656 | 0.88 | GPR35 (0.52) | GPR35TRPV1FABP4FABP5NTRK1 | |
| SCHEMBL1241406 | 0.78 | GPR35 (0.49) | GPR35TRPV1NTRK1IGF2BP2EPHX2 | |
| SCHEMBL14113041 | 0.77 | TMPRSS4 (0.59) | TRPV1NTRK1 | |
| SCHEMBL14113040 | 0.74 | TMPRSS4 (0.51) | NTRK1 | |
| SCHEMBL7254948 | 0.74 | KDM4E (0.54) | FABP4FABP5IDH2PTGDR2ALDH1A1 | |
| SCHEMBL4006444 | 0.73 | ABL1 (0.40) | IGF2BP2EPHX2AURKATPX2PTPN1 | |
| SCHEMBL4006520 | 0.73 | CHRM3 (0.40) | IGF2BP2EPHX2AURKATPX2PTPN1 | |
| SCHEMBL14113004 | 0.72 | SCN5A (0.50) | TRPV1SERPINE1PTGDR2 | |
| SCHEMBL4002954 | 0.72 | EPHX2 (0.47) | GPR35TRPV1IGF2BP2EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2072498-A1 | N-PHENYLOXAMIDIC ACID DERIVATIVE | Institute of Medicinal Molecular Design, Inc. (JP) | 2009-06-24 | — | — | EP | disclosed |