Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 12/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1889320 | 0.93 | AGTR1 (0.57) | AGTR1PPARGKCNH2 | |
| SCHEMBL1893788 | 0.83 | AGTR1 (0.56) | AGTR1PPARGKCNH2 | |
| SCHEMBL12349204 | 0.80 | AGTR1 (0.45) | AGTR1 | |
| SCHEMBL4314211 | 0.79 | AGTR1 (0.54) | AGTR1PPARG | |
| SCHEMBL1887274 | 0.79 | AGTR1 (0.59) | AGTR1PPARGKCNH2 | |
| SCHEMBL2877386 | 0.78 | AGTR1 (0.55) | AGTR1PPARGKCNH2 | |
| SCHEMBL4010292 | 0.78 | PPARG (0.53) | AGTR1PPARG | |
| SCHEMBL4310825 | 0.78 | AGTR1 (0.53) | AGTR1PPARGKCNH2 | |
| SCHEMBL1890924 | 0.78 | AGTR1 (0.56) | AGTR1PPARGKCNH2 | |
| SCHEMBL1889365 | 0.77 | AGTR1 (0.55) | AGTR1PPARGKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074117-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | disclosed |