Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 5/20 | 0.59 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.59 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.35 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27542658 | 0.77 | CPN1 (0.50) | CPN1CPB2GABRPGABRDGABRA1 | |
| SCHEMBL2353967 | 0.74 | CPN1 (1.00) | CPN1CPB2GABRPGABRDGABRA1 | |
| SCHEMBL2951918 | 0.71 | CPN1 (0.52) | CPN1CPB2GABRPGABRDGABRA1 | |
| SCHEMBL22295980 | 0.70 | CPN1 (0.41) | CPN1CPB2GABRPGABRDGABRA1 | |
| Hydrochloric Acid SCHEMBL3159633 | 0.70 | CPN1 (0.50) | CPN1CPB2GABRPGABRDGABRA1 | |
| Bicarbonate SCHEMBL28072717 | 0.69 | CPN1 (0.48) | CPN1CPB2GABRPGABRDGABRA1 | |
| SCHEMBL28301973 | 0.68 | CPN1 (0.48) | CPN1CPB2GABRPGABRDGABRA1 | |
| SCHEMBL4991489 | 0.68 | ALDH1A1 (0.40) | PMP22 | |
| Bicarbonate SCHEMBL28323252 | 0.67 | CPN1 (0.47) | CPN1CPB2GABRPGABRDGABRA1 | |
| Bicarbonate SCHEMBL28072663 | 0.67 | CPN1 (0.47) | CPN1CPB2GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009082340-A1 | METHOD FOR MONITORING THE PROGRESSION OF FIBRINOLYSIS'646 | ASTRAZENECA AB (SE) | 2009-07-02 | — | — | WO | disclosed |
| US-7071175-B1 | Pyridine mercapto carboxylic acids as carboxypeptidase U inhibitors | ASTRAZENECA AB (SE) | 2006-07-04 | — | — | US | disclosed |
| EP-1180098-A1 | NEW COMPOUNDS | AstraZeneca AB (SE) | 2002-02-20 | — | — | EP | disclosed |
| WO-2000066557-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 2000-11-09 | — | — | WO | disclosed |