Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL3356850 | 1.00 | — | — | |
| Bicarbonate SCHEMBL28760009 | 0.95 | ALDH1A1 (0.60) | — | |
| Bicarbonate SCHEMBL28807965 | 0.95 | ALDH1A1 (0.60) | — | |
| Bicarbonate SCHEMBL3833090 | 0.95 | ALDH1A1 (0.60) | — | |
| Bicarbonate SCHEMBL4489032 | 0.95 | — | — | |
| Bicarbonate SCHEMBL20299067 | 0.95 | ALDH1A1 (0.60) | — | |
| Bicarbonate SCHEMBL29281087 | 0.91 | — | — | |
| Bicarbonate SCHEMBL28253570 | 0.91 | — | — | |
| Bicarbonate SCHEMBL6375666 | 0.91 | — | — | |
| Bicarbonate SCHEMBL8555584 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692145-B1 | METHODS FOR PRODUCING COPPER ETHANOLAMINE SOLUTIONS | ARCH CHEM INC (US) | 2013-09-04 | — | — | EP | disclosed |
| EP-1692145-A4 | METHODS FOR PRODUCING COPPER ETHANOLAMINE SOLUTIONS | ARCH CHEM INC (US) | 2009-06-24 | — | — | EP | disclosed |
| CN-100360505-C | Quinazoline derivatives as angiogenesis inhibitors | ASTRAZENECA AB (SE) | 2008-01-09 | — | — | CN | disclosed |
| US-7273944-B2 | Methods for producing copper ethanolamine solutions | ARCH CHEMICALS, INC. (US) | 2007-09-25 | — | — | US | disclosed |
| EP-1692145-A1 | METHODS FOR PRODUCING COPPER ETHANOLAMINE SOLUTIONS | Arch Chemicals, Inc. (US) | 2006-08-23 | — | — | EP | disclosed |
| US-20050171369-A1 | Methods for producing copper ethanolamine solutions | ARCH CHEMICALS, INC. | 2005-08-04 | — | — | US | disclosed |
| CN-1633438-A | Process for the dissolution of copper metal | PHIBROTECH INC (US) | 2005-06-29 | — | — | CN | disclosed |
| WO-2005051961-A1 | METHODS FOR PRODUCING COPPER ETHANOLAMINE SOLUTIONS | ARCH CHEMICALS, INC. (US) | 2005-06-09 | — | — | WO | disclosed |
| CN-1597667-A | Quinazoline derivatives as angiogenesis inhibitors | ASTRAZENECA AB (SE) | 2005-03-23 | — | — | CN | disclosed |
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |