Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.67 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | RORB | Q92753 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5083539 | 0.82 | PPARG (0.80) | PPARGPPARASLC22A12MRGPRX4KDM4E | |
| SCHEMBL31053289 | 0.82 | PPARG (0.80) | PPARGPPARASLC22A12MRGPRX4KDM4E | |
| Metaglidasen SCHEMBL2443233 | 0.80 | PPARG (1.00) | PPARGPPARASLC22A12MRGPRX4KDM4E | |
| Metaglidasen SCHEMBL14606136 | 0.80 | PPARG (1.00) | PPARGPPARASLC22A12MRGPRX4KDM4E | |
| Mbx-102 Acid Form SCHEMBL12189837 | 0.80 | PPARG (1.00) | PPARGPPARASLC22A12MRGPRX4KDM4E | |
| Metaglidasen SCHEMBL29387584 | 0.80 | PPARG (1.00) | PPARGPPARASLC22A12MRGPRX4KDM4E | |
| Metaglidasen SCHEMBL11733289 | 0.79 | PPARG (0.97) | PPARGPPARASLC22A12MRGPRX4KDM4E | |
| SCHEMBL7823683 | 0.78 | PPARG (0.47) | PPARGPPARATLR8TLR7RORC | |
| SCHEMBL7823689 | 0.78 | PPARG (0.47) | PPARGPPARATLR8TLR7RORC | |
| SCHEMBL4576498 | 0.78 | PPARG (0.82) | PPARGPPARASLC22A12MRGPRX4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2775835-A1 | METHODS FOR TREATING GOUT IN PATIENT SUBPOPULATIONS | METABOLEX, INC. (US) | 2014-09-17 | — | — | EP | disclosed |
| WO-2013066352-A1 | METHODS FOR TREATING GOUT IN PATIENT SUBPOPULATIONS | METABOLEX, INC. (US) | 2013-05-10 | — | — | WO | disclosed |
| EP-1343493-A4 | USE OF(-) (3-HALOMETHYLPHENOXY) (4-HALOPHENYL) ACETIC ACID DERIVATIVES FOR TREATMENT OF INSULIN RESISTANCE, TYPE 2 DIABETES, HYPERLIPIDEMIA AND HYPERURICEMIA | METABOLEX INC (US) | 2009-06-24 | — | — | EP | disclosed |
| EP-1937620-A2 | RESOLUTION OF ALPHA-(PHENOXY) PHENYLACETIC ACID DERIVATIVES WITH NAPHTHYL-ALKYLAMINES | Metabolex Inc. (US) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007038277-A2 | RESOLUTION OF ALPHA-(PHENOXY) PHENYLACETIC ACID DERIVATIVES WITH NAPHTHYL-ALKYLAMINES | METABOLEX, INC. (US) | 2007-04-05 | — | — | WO | disclosed |
| EP-1343493-A2 | USE OF(-) (3-HALOMETHYLPHENOXY) (4-HALOPHENYL) ACETIC ACID DERIVATIVES FOR TREATMENT OF INSULIN RESISTANCE, TYPE 2 DIABETES, HYPERLIPIDEMIA AND HYPERURICEMIA | METABOLEX, INC. (US) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002044113-A9 | USE OF(-) (3-HALOMETHYLPHENOXY) (4-HALOPHENYL) ACETIC ACID DERIVATIVES FOR TREATMENT OF INSULIN RESISTANCE, TYPE 2 DIABETES, HYPERLIPIDEMIA AND HYPERURICEMIA | METABOLEX INC (US) | 2003-05-01 | — | — | WO | disclosed |
| WO-2002044113-A2 | USE OF(-) (3-HALOMETHYLPHENOXY) (4-HALOPHENYL) ACETIC ACID DERIVATIVES FOR TREATMENT OF INSULIN RESISTANCE, TYPE 2 DIABETES, HYPERLIPIDEMIA AND HYPERURICEMIA | METABOLEX, INC. (US) | 2002-06-06 | — | — | WO | disclosed |