SCHEMBL4009435

SCHEMBL4009435

CC(Cl)C(C#N)O[Si](C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
CYP3A4 P08684 1/20 0.30
ALOX15 P16050 1/20 0.30
HIF1A Q16665 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4009438 1.00 ALDH1A1 (0.30) ALDH1A1CYP3A4ALOX15HIF1ATSHR
SCHEMBL4009442 1.00 ALDH1A1 (0.30) ALDH1A1CYP3A4ALOX15HIF1ATSHR
SCHEMBL4007843 0.79
SCHEMBL4007841 0.79
SCHEMBL4014285 0.79
SCHEMBL4014289 0.79
SCHEMBL4009445 0.76
SCHEMBL4009447 0.76
SCHEMBL27701605 0.70
SCHEMBL5972395 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1926709-A4 PROCESS FOR THE PREPARATION OF CHIRAL 3-HYDROXY PYRROLIDINE COMPOUND AND DERIVATIVES THEREOF HAVING HIGH OPTICAL PURITY RSTECH CORP (KR) 2009-06-24 EP disclosed
EP-1926709-A1 PROCESS FOR THE PREPARATION OF CHIRAL 3-HYDROXY PYRROLIDINE COMPOUND AND DERIVATIVES THEREOF HAVING HIGH OPTICAL PURITY RStech Corporation (KR) 2008-06-04 EP disclosed
WO-2007024113-A1 PROCESS FOR THE PREPARATION OF CHIRAL 3-HYDROXY PYRROLIDINE COMPOUND AND DERIVATIVES THEREOF HAVING HIGH OPTICAL PURITY RSTECH CORPORATION (KR) 2007-03-01 WO disclosed