SCHEMBL4009626

SCHEMBL4009626

COCCCCC(COC)OC

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
PRKD3 O94806 1/20 0.32
PRKCG P05129 1/20 0.32
PRKCB P05771 1/20 0.32
PRKCA P17252 1/20 0.32
PRKCH P24723 1/20 0.32
PRKCI P41743 1/20 0.32
PRKCE Q02156 1/20 0.32
PRKCQ Q04759 1/20 0.32
PRKCZ Q05513 1/20 0.32
PRKCD Q05655 1/20 0.32
PRKD1 Q15139 1/20 0.32
LPAR6 P43657 3/20 0.32
LPAR1 Q92633 3/20 0.32
LPAR4 Q99677 3/20 0.32
LPAR5 Q9H1C0 3/20 0.32
LPAR2 Q9HBW0 3/20 0.32
LPAR3 Q9UBY5 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8859008 0.90 PRKD3 (0.34) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL22590736 0.90 ALDH1A1 (0.36) ALDH1A1PRKD3PRKCGPRKCBPRKCA
SCHEMBL22590734 0.87 ALDH1A1 (0.39) ALDH1A1PRKD3PRKCGPRKCBPRKCA
SCHEMBL28410830 0.86 ALDH1A1 (0.35) ALDH1A1LPAR6LPAR1LPAR4LPAR5
SCHEMBL22590863 0.84 ALDH1A1 (0.34) ALDH1A1
SCHEMBL19545978 0.83 PRKD3 (0.43) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL22590889 0.82 ALDH1A1 (0.38) ALDH1A1LPAR6LPAR1LPAR4LPAR5
SCHEMBL12580946 0.81 CYP2C9 (0.30)
SCHEMBL24554817 0.81 CYP3A4 (0.33)
SCHEMBL10530614 0.81 PRKD3 (0.46) PRKD3PRKCGPRKCBPRKCAPRKCH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150291892-A1 LOW TEMPERATURE, LOW PRESSURE UPGRADING AND STABILIZATION OF BIO-OIL OR BIO-OIL FRACTIONS IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2015-10-15 US disclosed
WO-2009079551-A1 HETEROGENEOUS PROMOTION OF OXIRANE HYDROFORMYLATION SHELL OIL COMPANY (US) 2009-06-25 WO disclosed
US-20090163742-A1 HETEROGENEOUS PROMOTION OF OXIRANE HYDROFORMYLATION SHELL OIL COMPANY 2009-06-25 US disclosed
CN-1045202-C Process for making 1,3-diols and 3-hydroxyaldehydes SHELL INT RESEARCH (NL) 1999-09-22 CN disclosed
EP-0682650-B1 PROCESS FOR MAKING 1,3-DIOLS AND 3-HYDROXYALDEHYDES SHELL INT RESEARCH (NL) 1998-05-20 EP disclosed
CN-1117289-A Process for making 1,3-diols and 3-hydroxyaldehydes SHELL INT RESEARCH (NL) 1996-02-21 CN disclosed
EP-0682650-A1 PROCESS FOR MAKING 1,3-DIOLS AND 3-HYDROXYALDEHYDES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1995-11-22 EP disclosed
EP-0478850-B1 Process for the preparation of beta-hydroxy aldehydes SHELL INT RESEARCH (NL) 1994-09-14 EP disclosed
US-5344993-A Catalytic hydroformylation of epoxides with di-tert-phosphines SHELL OIL COMPANY (US) 1994-09-06 US disclosed
WO-1994018149-A1 PROCESS FOR MAKING 1,3-DIOLS AND 3-HYDROXYALDEHYDES SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 1994-08-18 WO disclosed
US-5304686-A Hydroformylating ethylene oxide using ditertiary phosphine modified cobalt carbonyl catalysts; further hydrogenation SHELL OIL COMPANY (US) 1994-04-19 US disclosed
US-5304691-A Hydroformylation og ethylene oxide SHELL OIL COMPANY (US) 1994-04-19 US disclosed
US-5256827-A Process for making 3-hydroxypropanal and 1,3-propanediol SHELL OIL COMPANY (US) 1993-10-26 US disclosed
EP-0478850-A1 Process for the preparation of beta-hydroxy aldehydes SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-04-08 EP disclosed