Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 6/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | LYN | P07948 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | BLK | P51451 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1241535 | 0.91 | ABL1 (0.46) | ABL1KCNH2L3MBTL1EPHX2POLB | |
| SCHEMBL4006520 | 0.82 | CHRM3 (0.40) | EPHX2FFAR4 | |
| SCHEMBL12907207 | 0.79 | C5AR1 (0.53) | ABL1PPARDFFAR4 | |
| SCHEMBL1241755 | 0.79 | ABL1 (0.50) | ABL1KCNH2EPHX2LCKFYN | |
| SCHEMBL4006770 | 0.77 | EPHX2 (0.45) | ABL1L3MBTL1EPHX2KMT2AMEN1 | |
| SCHEMBL1241636 | 0.76 | NOS3 (0.36) | ABL1LCKFYNCSF1RLYN | |
| SCHEMBL13580916 | 0.76 | ABL1 (0.59) | ABL1KCNH2L3MBTL1EPHX2LCK | |
| SCHEMBL1242849 | 0.75 | ABL1 (0.46) | ABL1KCNH2L3MBTL1EPHX2LCK | |
| SCHEMBL1239679 | 0.75 | ABL1 (0.46) | ABL1KCNH2L3MBTL1EPHX2LCK | |
| SCHEMBL1241471 | 0.74 | CYP19A1 (0.46) | POLBKMT2AMEN1GAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2072498-A1 | N-PHENYLOXAMIDIC ACID DERIVATIVE | Institute of Medicinal Molecular Design, Inc. (JP) | 2009-06-24 | — | — | EP | disclosed |