Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 18/20 | 0.62 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4004440 | 0.84 | TTK (0.52) | — | |
| SCHEMBL4008935 | 0.84 | FGFR1 (0.56) | ITKFGFR1 | |
| SCHEMBL4011763 | 0.81 | ITK (0.57) | ITKFGFR1 | |
| SCHEMBL1460612 | 0.80 | ITK (0.80) | ITK | |
| SCHEMBL4014470 | 0.79 | TTK (0.41) | ITK | |
| SCHEMBL4008237 | 0.78 | ITK (0.53) | ITKFGFR1TRPA1 | |
| SCHEMBL141981 | 0.78 | ITK (1.00) | ITKTRPA1 | |
| SCHEMBL4008264 | 0.78 | TTK (0.43) | ITK | |
| SCHEMBL4004563 | 0.78 | TTK (0.41) | ITK | |
| SCHEMBL4008249 | 0.78 | TTK (0.41) | ITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473701-B2 | Substituted indazoles, compositions containing them, method of production and use | AVENTIS PHARMA S.A. (FR) | 2009-01-06 | — | — | US | claimed |