Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 19/20 | 0.57 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4008237 | 0.84 | ITK (0.53) | ITKFGFR1 | |
| SCHEMBL4007930 | 0.83 | TTK (0.56) | — | |
| SCHEMBL4008935 | 0.82 | FGFR1 (0.56) | ITKFGFR1 | |
| SCHEMBL4008142 | 0.82 | PDPK1 (0.60) | ITKFGFR1 | |
| SCHEMBL3928624 | 0.81 | ITK (0.49) | ITKFGFR1 | |
| SCHEMBL4010511 | 0.81 | ITK (0.62) | ITKFGFR1 | |
| SCHEMBL4006913 | 0.80 | ITK (0.66) | ITK | |
| SCHEMBL4004255 | 0.79 | CYP1A2 (0.39) | — | |
| SCHEMBL4003706 | 0.78 | TTK (0.37) | — | |
| SCHEMBL4006912 | 0.78 | MEN1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473701-B2 | Substituted indazoles, compositions containing them, method of production and use | AVENTIS PHARMA S.A. (FR) | 2009-01-06 | — | — | US | claimed |
| US-7473701-B2 | Substituted indazoles, compositions containing them, method of production and use | AVENTIS PHARMA S.A. (FR) | 2009-01-06 | — | — | US | disclosed |