Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4010574 | 1.00 | TP53 (0.36) | TP53CYP3A4MAPTCASP1BLM | |
| SCHEMBL4001393 | 0.88 | TP53 (0.36) | TP53CYP3A4MAPTCASP1BLM | |
| SCHEMBL13808731 | 0.88 | TP53 (0.36) | TP53CYP3A4MAPTCASP1BLM | |
| SCHEMBL4001397 | 0.88 | TP53 (0.36) | TP53CYP3A4MAPTCASP1BLM | |
| SCHEMBL4007165 | 0.86 | TP53 (0.34) | TP53CYP3A4MAPTCASP1BLM | |
| SCHEMBL4007164 | 0.86 | TP53 (0.34) | TP53CYP3A4MAPTCASP1BLM | |
| SCHEMBL13808911 | 0.85 | PABPC1 (0.39) | TP53CYP3A4MAPTCASP1BLM | |
| SCHEMBL4003863 | 0.85 | PABPC1 (0.39) | TP53CYP3A4MAPTCASP1BLM | |
| SCHEMBL11623627 | 0.84 | TP53 (0.34) | TP53CYP3A4MAPTCASP1BLM | |
| SCHEMBL13808735 | 0.82 | MALT1 (0.41) | TP53CYP3A4MAPTCASP1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009077394-A1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF THESE DYES OBTAINED FROM 5-(2-HYDROXYETHYLAMINO)-2-METHYLPHENOL, AND DYEING PROCESS USING THESE DYES AND PRECURSORS | L'OREAL (FR) | 2009-06-25 | — | — | WO | disclosed |