Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.90 |
| ▸ | EPHX2 | P34913 | 9/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5950609 | 1.00 | HSD11B1 (0.90) | HSD11B1EPHX2RAB9ATSHR | |
| SCHEMBL4010674 | 1.00 | HSD11B1 (0.90) | HSD11B1EPHX2RAB9ATSHR | |
| SCHEMBL5950314 | 1.00 | HSD11B1 (0.90) | HSD11B1EPHX2RAB9ATSHR | |
| SCHEMBL4007664 | 1.00 | HSD11B1 (0.90) | HSD11B1EPHX2RAB9ATSHR | |
| SCHEMBL4006568 | 0.99 | HSD11B1 (0.88) | HSD11B1EPHX2RAB9A | |
| SCHEMBL4006575 | 0.99 | HSD11B1 (0.88) | HSD11B1EPHX2RAB9A | |
| SCHEMBL4142798 | 0.96 | HSD11B1 (0.90) | HSD11B1EPHX2RAB9ATSHR | |
| SCHEMBL613129 | 0.95 | HSD11B1 (1.00) | HSD11B1EPHX2RAB9ATSHR | |
| SCHEMBL4961348 | 0.95 | HSD11B1 (1.00) | HSD11B1EPHX2RAB9ATSHR | |
| SCHEMBL612171 | 0.95 | HSD11B1 (1.00) | HSD11B1EPHX2RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778229-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-06-17 | — | — | EP | claimed |
| EP-1778229-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-05-02 | — | — | EP | claimed |
| WO-2006020598-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-23 | — | — | WO | claimed |
| EP-1778229-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-1778229-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006020598-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-23 | — | — | WO | disclosed |