Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.55 |
| ▸ | CA1 | P00915 | 8/20 | 0.55 |
| ▸ | CA4 | P22748 | 3/20 | 0.55 |
| ▸ | CA6 | P23280 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 7/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6121437 | 0.83 | CA1 (0.45) | CA2CA1CA4CA6CA9 | |
| SCHEMBL28142430 | 0.81 | CA1 (0.44) | CA2CA1CA4CA6CA9 | |
| SCHEMBL3853245 | 0.80 | CA1 (0.46) | CA2CA1CA4CA6CA9 | |
| SCHEMBL3837671 | 0.80 | CA1 (0.42) | CA2CA1CA4CA6CA9 | |
| SCHEMBL15652451 | 0.80 | CA2 (0.42) | CA2CA1CA4CA6CA9 | |
| SCHEMBL31371139 | 0.78 | CA2 (0.57) | CA2CA1CA4CA6CA9 | |
| SCHEMBL30988960 | 0.78 | CA1 (0.41) | CA2CA1CA4CA6CA9 | |
| SCHEMBL9108195 | 0.77 | CA2 (0.55) | CA2CA1CA4CA6CA9 | |
| SCHEMBL4690711 | 0.76 | KMT2A (0.48) | CA2CA1CA4CA6CA9 | |
| SCHEMBL7520955 | 0.76 | CA2 (0.46) | CA2CA1CA4CA6CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080722-A2 | CARBOXYLIC DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2009-07-02 | — | — | WO | disclosed |