Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.52 |
| ▸ | RELA | Q04206 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | GPER1 | Q99527 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13768811 | 0.88 | ABL1 (0.58) | ABL1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL13768200 | 0.87 | ABL1 (0.57) | ABL1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL4012042 | 0.86 | ABL1 (0.56) | ABL1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL4010872 | 0.86 | ABL1 (0.56) | ABL1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL4009561 | 0.84 | NPC1 (0.55) | ABL1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL4015480 | 0.84 | ABL1 (0.60) | ABL1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL4010576 | 0.78 | MEN1 (0.58) | ABL1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL4010897 | 0.78 | MEN1 (0.58) | ABL1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL13768201 | 0.77 | RAB9A (0.52) | ABL1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL4006976 | 0.76 | ABL1 (0.58) | ABL1LMNAMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009085256-A1 | ANTI-HIV COMPOUNDS | PANACOS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009085256-A1 | ANTI-HIV COMPOUNDS | PANACOS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |