Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 15/20 | 0.52 |
| ▸ | CNR1 | P21554 | 7/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 2/20 | 0.35 |
| ▸ | KRAS | P01116 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1619715 | 0.83 | CNR2 (0.51) | CNR2CNR1NTRK1MAPTXBP1 | |
| SCHEMBL1621259 | 0.80 | CNR2 (0.53) | CNR2CNR1 | |
| SCHEMBL1621602 | 0.78 | CNR2 (0.83) | CNR2CNR1 | |
| SCHEMBL4016691 | 0.75 | MAPT (0.49) | CNR2CNR1NTRK1MAPTXBP1 | |
| SCHEMBL766858 | 0.74 | CNR2 (0.57) | CNR2CNR1NTRK1MAPT | |
| SCHEMBL4017564 | 0.73 | CNR2 (0.74) | CNR2CNR1 | |
| SCHEMBL1621382 | 0.73 | CNR2 (0.73) | CNR2CNR1 | |
| SCHEMBL1621173 | 0.73 | CNR2 (0.72) | CNR2CNR1 | |
| SCHEMBL10217739 | 0.72 | CNR2 (0.78) | CNR2CNR1 | |
| SCHEMBL1620767 | 0.71 | CNR2 (0.69) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074084-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-01 | — | — | EP | claimed |
| WO-2008039645-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-04-03 | — | — | WO | claimed |