Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.38 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1619715 | 0.91 | CNR2 (0.51) | MAPTXBP1NPSR1CNR2CNR1 | |
| SCHEMBL1621889 | 0.84 | CNR2 (0.53) | MAPTCNR2CNR1L3MBTL1 | |
| SCHEMBL1619666 | 0.77 | CNR2 (0.50) | MAPTXBP1NPSR1CNR2CNR1 | |
| SCHEMBL1621477 | 0.76 | CNR2 (0.53) | MAPTXBP1NPSR1CNR2CNR1 | |
| SCHEMBL1621245 | 0.76 | CNR2 (0.54) | MAPTXBP1NPSR1CNR2CNR1 | |
| SCHEMBL766858 | 0.75 | CNR2 (0.57) | MAPTCNR2CNR1NTRK1 | |
| SCHEMBL4010942 | 0.75 | CNR2 (0.52) | MAPTXBP1NPSR1CNR2CNR1 | |
| SCHEMBL1621068 | 0.75 | CNR2 (0.56) | CNR2CNR1 | |
| SCHEMBL1620692 | 0.74 | CNR2 (0.48) | CNR2CNR1TRPV4NTRK1KCNJ6 | |
| SCHEMBL1620571 | 0.72 | MAPT (0.52) | MAPTXBP1NPSR1NTRK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074084-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008039645-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-04-03 | — | — | WO | disclosed |