SCHEMBL4010986

SCHEMBL4010986

CCCCc1nc(C)c(Cc2ccccc2O)c(=O)n1Cc1ccc(-c2ccccc2C#N)cc1

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 11/20 0.51
AGTR1 P30556 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4013409 0.90 PPARG (0.52) PPARGAGTR1
SCHEMBL9844021 0.88 PPARG (0.59) PPARGAGTR1
SCHEMBL9843724 0.88 PPARG (0.59) PPARGAGTR1
SCHEMBL9843820 0.87 PPARG (0.57) PPARGAGTR1
SCHEMBL9843828 0.84 PPARG (0.56) PPARGAGTR1
SCHEMBL9843803 0.84 PPARG (0.58) PPARGAGTR1
SCHEMBL1892044 0.83 PPARG (0.61) PPARGAGTR1
SCHEMBL1895410 0.83 PPARG (0.56) PPARGAGTR1
SCHEMBL4012267 0.83 PPARG (0.73) PPARGAGTR1
SCHEMBL1887811 0.83 PPARG (0.50) PPARGAGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009133970-A1 CRYSTALLINE COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-11-05 WO disclosed
EP-2074117-A2 HETEROMONOCYCLIC COMPOUND AND USE THEREOF Takeda Pharmaceutical Company Limited (JP) 2009-07-01 EP disclosed
WO-2008062905-A2 HETEROMONOCYCLIC COMPOUND AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-05-29 WO disclosed