Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.57 |
| ▸ | APLNR | P35414 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843828 | 0.95 | PPARG (0.56) | PPARGAPLNRACHEAGTR1 | |
| SCHEMBL9844347 | 0.93 | PPARG (0.56) | PPARGAPLNRACHEAGTR1 | |
| SCHEMBL9844021 | 0.89 | PPARG (0.59) | PPARGAGTR1 | |
| SCHEMBL9843724 | 0.89 | PPARG (0.59) | PPARGAGTR1 | |
| SCHEMBL9843803 | 0.87 | PPARG (0.58) | PPARGACHEAGTR1 | |
| SCHEMBL4010986 | 0.87 | PPARG (0.51) | PPARGAGTR1 | |
| SCHEMBL1894638 | 0.85 | PPARG (0.56) | PPARGACHEAGTR1 | |
| SCHEMBL1895410 | 0.85 | PPARG (0.56) | PPARGAGTR1 | |
| SCHEMBL9844258 | 0.84 | PDE4A (0.69) | PPARGAGTR1 | |
| SCHEMBL1887811 | 0.84 | PPARG (0.50) | PPARGAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407342-A2 | Pyrimidine derivatives | CIBA-GEIGY AG (CH) | 1991-01-09 | — | — | EP | disclosed |