Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31490341 | 1.00 | MMP12 (0.70) | MMP12MMP13 | |
| SCHEMBL31490108 | 0.90 | MMP12 (0.67) | MMP12MMP13 | |
| SCHEMBL4013010 | 0.90 | MMP12 (0.67) | MMP12MMP13 | |
| SCHEMBL4164972 | 0.87 | MMP12 (0.60) | MMP12MMP13 | |
| SCHEMBL31490246 | 0.87 | MMP12 (0.60) | MMP12MMP13 | |
| SCHEMBL4017184 | 0.87 | MMP12 (0.64) | MMP12MMP13 | |
| SCHEMBL4158583 | 0.84 | MMP12 (0.67) | MMP12MMP13 | |
| SCHEMBL31490421 | 0.84 | MMP12 (0.67) | MMP12MMP13 | |
| SCHEMBL4008382 | 0.84 | MMP12 (0.67) | MMP12MMP13 | |
| SCHEMBL4012002 | 0.84 | MMP12 (0.67) | MMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074107-A2 | TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS | Wyeth a Corporation of the State of Delaware (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008057254-A2 | TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS | WYETH (US) | 2008-05-15 | — | — | WO | disclosed |
| WO-2008057254-A2 | TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS | WYETH (US) | 2008-05-15 | — | — | WO | disclosed |