Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 14/20 | 0.45 |
| ▸ | RORC | P51449 | 2/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27971365 | 0.84 | ELANE (0.54) | ELANERORCRARGF2PLAU | |
| SCHEMBL11749311 | 0.78 | ELANE (0.49) | ELANERORCF2PLAUKDM4E | |
| SCHEMBL9952327 | 0.78 | ELANE (0.45) | ELANERORCF2PLAUKDM4E | |
| SCHEMBL1514915 | 0.78 | ELANE (0.60) | ELANERORCF2PLAUKDM4E | |
| SCHEMBL27578607 | 0.78 | ELANE (0.45) | ELANERORCRARGF2PLAU | |
| SCHEMBL27758519 | 0.78 | ELANE (0.57) | ELANERORCF2PLAU | |
| SCHEMBL11897866 | 0.77 | ESR1 (0.38) | HSD17B10MEN1KMT2A | |
| SCHEMBL7016168 | 0.76 | L3MBTL1 (0.44) | ELANEF2PLAUMEN1KMT2A | |
| SCHEMBL5331216 | 0.75 | ELANE (0.43) | ELANERORCRARGF2PLAU | |
| SCHEMBL23782714 | 0.74 | ELANE (0.49) | ELANEF2PLAUKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106170486-B | Novel indazolecarboxamides, method for the production thereof, pharmaceutical preparations containing the same and use thereof for producing medicaments | 拜耳医药股份有限公司 | 2019-01-15 | — | — | CN | disclosed |
| CN-101553492-A | RAF inhibitor compounds and methods of use thereof | ARRAY BIOPHARMA INC (US) | 2009-10-07 | — | — | CN | disclosed |
| WO-2009009411-A1 | SUBSTITUTED HETEROCYCLIC ETHERS AND THEIR USE IN CNS DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-01-15 | — | — | WO | disclosed |