Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 6/20 | 0.49 |
| ▸ | CNR2 | P34972 | 4/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1621617 | 0.92 | CNR2 (0.50) | GCKCNR2CNR1LMNAALDH1A1 | |
| SCHEMBL775578 | 0.91 | GCK (0.56) | GCKCNR2CNR1ATAD2NPC1 | |
| SCHEMBL1621911 | 0.83 | CNR2 (0.54) | GCKCNR2CNR1ATAD2 | |
| SCHEMBL4013140 | 0.81 | CNR2 (0.54) | GCKCNR2CNR1ATAD2NPC1 | |
| SCHEMBL1620978 | 0.79 | ADORA1 (0.59) | GCKCNR2CNR1LMNAKDM4E | |
| SCHEMBL1619549 | 0.77 | TMIGD3 (0.53) | GCKCNR2CNR1ATAD2LMNA | |
| SCHEMBL1621078 | 0.77 | CNR2 (0.49) | GCKCNR2CNR1NPC1RAB9A | |
| SCHEMBL1620080 | 0.77 | CNR2 (0.54) | GCKCNR2CNR1ATAD2NPC1 | |
| SCHEMBL1621081 | 0.76 | GCK (0.57) | GCKCNR2CNR1NPC1RAB9A | |
| SCHEMBL1619362 | 0.76 | GCK (0.49) | GCKCNR2CNR1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074084-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008039645-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-04-03 | — | — | WO | disclosed |