Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 15/20 | 0.54 |
| ▸ | CNR1 | P21554 | 9/20 | 0.54 |
| ▸ | GCK | P35557 | 1/20 | 0.48 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL775578 | 0.90 | GCK (0.56) | CNR2CNR1GCKATAD2SMN1; SMN2 | |
| SCHEMBL775524 | 0.89 | CNR2 (0.62) | CNR2CNR1EGFRSMN1; SMN2NPC1 | |
| SCHEMBL4011827 | 0.88 | CNR2 (0.52) | CNR2CNR1GCKATAD2EGFR | |
| SCHEMBL1619534 | 0.83 | CNR2 (0.55) | CNR2CNR1EGFRSMN1; SMN2NPC1 | |
| SCHEMBL1620815 | 0.83 | CNR2 (0.55) | CNR2CNR1EGFRSMN1; SMN2NPC1 | |
| SCHEMBL4163893 | 0.83 | CNR2 (0.58) | CNR2CNR1EGFRSMN1; SMN2NPC1 | |
| SCHEMBL1621911 | 0.82 | CNR2 (0.54) | CNR2CNR1GCKATAD2 | |
| SCHEMBL4011214 | 0.81 | GCK (0.49) | CNR2CNR1GCKATAD2SMN1; SMN2 | |
| SCHEMBL1619580 | 0.81 | CNR2 (0.53) | CNR2CNR1EGFRSMN1; SMN2NPC1 | |
| SCHEMBL10216975 | 0.80 | CNR2 (0.70) | CNR2CNR1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074084-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-01 | — | — | EP | claimed |
| WO-2008039645-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-04-03 | — | — | WO | claimed |