Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.71 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3936641 | 0.85 | FAAH (0.71) | FAAHPROKR1LMNAPKMTNF | |
| SCHEMBL4017621 | 0.85 | FAAH (0.71) | FAAHPROKR1FPR2LMNATNF | |
| SCHEMBL3940445 | 0.85 | FAAH (0.84) | FAAHKDM4ESMN1; SMN2LMNAMEN1 | |
| SCHEMBL4017229 | 0.85 | FAAH (0.70) | FAAHPROKR1FPR2LMNATNF | |
| SCHEMBL3943336 | 0.84 | FAAH (0.77) | FAAHPROKR1KDM4ELMNAGRM4 | |
| SCHEMBL3933957 | 0.84 | FAAH (0.77) | FAAHSMN1; SMN2LMNAALDH1A1MAPK1 | |
| SCHEMBL3938849 | 0.84 | FAAH (0.77) | FAAHPROKR1LMNAPKMALDH1A1 | |
| SCHEMBL3930701 | 0.84 | FAAH (0.86) | FAAHKDM4ESMN1; SMN2LMNAMEN1 | |
| SCHEMBL3931443 | 0.84 | FAAH (0.77) | FAAHKDM4ELMNAGRM4TNF | |
| SCHEMBL3936894 | 0.84 | FAAH (0.79) | FAAHKDM4ELMNATNFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |