Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL766882 | 0.89 | KMT2A (0.49) | SMN1; SMN2MEN1KMT2AALDH1A1POLB | |
| SCHEMBL766943 | 0.89 | CNR2 (0.58) | CNR2MAPK14MAPTLMNAMAPK13 | |
| SCHEMBL1620986 | 0.78 | CNR2 (0.66) | CNR2MAPK14MAPTLMNAMAPK13 | |
| SCHEMBL1621065 | 0.78 | NPC1 (0.53) | SMN1; SMN2MEN1KMT2AALDH1A1POLB | |
| SCHEMBL3967832 | 0.77 | CNR2 (0.55) | CNR2SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL1621655 | 0.75 | CNR2 (0.55) | CNR2MAPK14MAPTLMNAMAPK13 | |
| SCHEMBL1621118 | 0.74 | CNR2 (0.64) | CNR2MAPK14MAPTLMNAMAPK13 | |
| SCHEMBL3661395 | 0.73 | ATAD2 (0.49) | SMN1; SMN2MEN1KMT2AALDH1A1POLB | |
| SCHEMBL1621453 | 0.72 | ATAD2 (0.48) | CNR2SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL1621510 | 0.72 | CNR2 (0.59) | CNR2MAPK14MAPTLMNAMAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074084-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008039645-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-04-03 | — | — | WO | disclosed |