SCHEMBL4011389

SCHEMBL4011389

CC(NC(N)=O)NC(N)=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.47
TSHR P16473 3/20 0.47
CA2 P00918 3/20 0.47
NFKB1 P19838 2/20 0.47
BLM P54132 2/20 0.47
PMP22 Q01453 2/20 0.47
CA9 Q16790 2/20 0.47
CYP3A4 P08684 1/20 0.47
CA5A P35218 1/20 0.47
ALDH1A1 P00352 2/20 0.41
NPC1 O15118 1/20 0.41
CYP1A2 P05177 1/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
THPO P40225 1/20 0.39
DPP4 P27487 3/20 0.39
CRBN Q96SW2 1/20 0.38
DPP8 Q6V1X1 2/20 0.36
DPP9 Q86TI2 2/20 0.36
FAP Q12884 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24892693 0.85
SCHEMBL8862265 0.81 TSHR (0.36) LMNATSHRCA2NFKB1BLM
SCHEMBL28609466 0.81 TGFBR1 (0.42) LMNATSHRCA2NFKB1BLM
SCHEMBL24463 0.80
SCHEMBL2448286 0.78
SCHEMBL1938866 0.78
SCHEMBL27662 0.78
Hydrochloric Acid SCHEMBL11795328 0.78
SCHEMBL1228638 0.78 NPC1 (0.40) LMNATSHRCA2NFKB1BLM
SCHEMBL31144892 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879989-A1 FABRIC CARE COMPOSITION COMPRISING POLYMER ENCAPSULATED FABRIC OR SKIN BENEFICIATING INGREDIENT Colgate-Palmolive Company (US) 2008-01-23 EP claimed
WO-2006121639-A1 FABRIC CARE COMPOSITION COMPRISING POLYMER ENCAPSULATED FABRIC OR SKIN BENEFICIATING INGREDIENT COLGATE-PALMOLIVE COMPANY (US) 2006-11-16 WO claimed
EP-1740682-B1 FABRIC CARE COMPOSITION COMPRISING POLYMER ENCAPSULATED FABRIC OR SKIN BENEFICIATING INGREDIENT COLGATE PALMOLIVE CO (US) 2009-06-24 EP disclosed
US-20080076698-A1 Fabric Care Composition Comprising Polymer Encapsulated Fabric or Skin Beneficiating Ingredient JACQUES ALAIN 2008-03-27 US disclosed
US-20080076697-A1 FABRIC CARE COMPOSITION COMPRISING POLYMER ENCAPSULATED FABRIC OR SKIN BENEFICIATING INGREDIENT HEIBEL MARIJA 2008-03-27 US disclosed
US-20080070824-A1 FABRIC CARE COMPOSITION COMPRISING POLYMER ENCAPSULATED FABRIC OR SKIN BENEFICIATING INGREDIENT HEIBEL MARIJA 2008-03-20 US disclosed
US-20080044390-A1 Methods and compositions for the treatment of neurodegenerative disorders CHDI, INCORPORATED 2008-02-21 US disclosed
EP-1879989-A1 FABRIC CARE COMPOSITION COMPRISING POLYMER ENCAPSULATED FABRIC OR SKIN BENEFICIATING INGREDIENT Colgate-Palmolive Company (US) 2008-01-23 EP disclosed
US-7304026-B2 Fabric care composition comprising polymer encapsulated fabric or skin beneficiating ingredient COLGATE-PALMOLIVE COMPANY (US) 2007-12-04 US disclosed
US-20070173433-A1 Fabric Care Composition Comprising Polymer Encapsulated Fabric or Skin Beneficiating Ingredient COLGATE-PALMOLIVE COMPANY 2007-07-26 US disclosed
US-7211556-B2 Fabric care composition comprising polymer encapsulated fabric or skin beneficiating ingredient COLGATE-PALMOLIVE COMPANY (US) 2007-05-01 US disclosed
EP-1290120-B1 FABRIC SOFTENING COMPOSITIONS CONTAINING CATIONIC SOFTENERS AND FATTY AMIDES COLGATE PALMOLIVE CO (US) 2006-05-17 EP disclosed
US-20050256027-A1 Fabric care composition comprising polymer encapsulated fabric or skin beneficiating ingredient COLGATE-PALMOLIVE COMPANY 2005-11-17 US disclosed
WO-2005103215-A1 FABRIC CARE COMPOSITION COMPRISING POLYMER ENCAPSULATED FABRIC OR SKIN BENEFICIATING INGREDIENT COLGATE-PALMOLIVE COMPANY (US) 2005-11-03 WO disclosed
WO-2005103216-A1 FABRIC CARE COMPOSITION COMPRISING POLYMER ENCAPSULATED FABRIC OR SKIN BENEFICIATING INGREDIENT COLGATE-PALMOLIVE COMPANY (US) 2005-11-03 WO disclosed
US-20050233939-A1 Fabric care composition comprising polymer encapsulated fabric or skin beneficiating ingredient COLGATE-PALMOLIVE COMPANY 2005-10-20 US disclosed
EP-1290120-A2 FABRIC SOFTENING COMPOSITIONS CONTAINING CATIONIC SOFTENERS AND FATTY AMIDES Colgate-Palmolive Company (US) 2003-03-12 EP disclosed
WO-2001092446-A2 FABRIC SOFTENING COMPOSITIONS CONTAINING CATIONIC SOFTENERS AND FATTY AMIDES COLGATE-PALMOLIVE COMPANY (US) 2001-12-06 WO disclosed
US-6191101-B1 CATIONIC SURFACTANTS, FATTY AMIDE, POLYSILOXANES AND WATER COLGATE-PALMOLIVE CO. 2001-02-20 US disclosed
US-3940365-A PHENOLIC ANTIOXIDANT AND AN UREA OR AN OXALIC ACID DIAMIDE OR AN AZODICARBOXYLIC AMIDE HOECHST AKTIENGESELLSCHAFT (DT) 1976-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080044390-A1 Methods and compositions for the treatment of neurodegenerative disorders HTT, SNCA, NLN LMNA 415/4885TSHR 4669/4885CA2 2424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.