Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4306420 | 0.90 | PPARG (0.52) | PPARGAGTR1ACHEAGTR2 | |
| SCHEMBL1891409 | 0.88 | PPARG (0.52) | PPARGAGTR1AGTR2 | |
| SCHEMBL4012577 | 0.84 | PPARG (0.57) | PPARGAGTR1ACHEAGTR2 | |
| SCHEMBL4012893 | 0.84 | PPARG (0.51) | PPARGAGTR1ACHEAGTR2 | |
| SCHEMBL4016260 | 0.83 | PPARG (0.52) | PPARGAGTR1ACHE | |
| SCHEMBL4016898 | 0.83 | PPARG (0.54) | PPARGAGTR1ACHE | |
| SCHEMBL4007590 | 0.83 | PPARG (0.53) | PPARGAGTR1ACHE | |
| SCHEMBL4009893 | 0.81 | PPARG (0.51) | PPARGAGTR1AGTR2 | |
| SCHEMBL4013600 | 0.79 | PPARG (0.49) | PPARGAGTR1ACHEAGTR2 | |
| SCHEMBL4010668 | 0.79 | PPARG (0.63) | PPARGAGTR1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133970-A1 | CRYSTALLINE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-05 | — | — | WO | disclosed |
| EP-2074117-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | disclosed |