Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | VEGFA | P15692 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13547786 | 0.76 | CA1 (0.54) | CA1CA2CA9PTGDR2PARP1 | |
| SCHEMBL30635417 | 0.76 | CA2 (0.54) | CA1CA2CA9PTGDR2PARP1 | |
| SCHEMBL1155659 | 0.76 | CA9 (0.59) | CA1CA2CA9PTGDR2CA12 | |
| SCHEMBL10444145 | 0.76 | CA2 (0.54) | CA1CA2CA9PTGDR2PARP1 | |
| SCHEMBL24141272 | 0.76 | CA1 (0.50) | CA1CA2CA9PTGDR2PARP1 | |
| SCHEMBL7873031 | 0.76 | CA2 (0.37) | CA1CA2CA9PARP1PARP10 | |
| SCHEMBL21028030 | 0.73 | CA2 (0.51) | CA1CA2CA9PTGDR2KDM4E | |
| SCHEMBL10199637 | 0.72 | CA1 (0.50) | CA1CA2CA9 | |
| SCHEMBL10443651 | 0.72 | CA9 (0.50) | CA1CA2CA9PTGDR2CA12 | |
| SCHEMBL14456114 | 0.72 | CA1 (0.50) | CA1CA2CA9PTGDR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074098-A2 | QUINOLINE COMPOUNDS | Wyeth (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008049047-A2 | QUINOLINE COMPOUNDS | WYETH (US) | 2008-04-24 | — | — | WO | disclosed |