Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.52 |
| ▸ | CNR2 | P34972 | 9/20 | 0.52 |
| ▸ | CNR1 | P21554 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.41 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.41 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.41 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.41 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.41 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1619672 | 0.94 | CNR2 (0.56) | TRPV1CNR2CNR1NPC1SMN1; SMN2 | |
| SCHEMBL4009816 | 0.85 | MAPT (0.54) | CNR2CNR1NPC1SMN1; SMN2KDM4E | |
| SCHEMBL1621245 | 0.85 | CNR2 (0.54) | CNR2CNR1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL4015482 | 0.83 | CNR2 (0.43) | TRPV1CNR2CNR1SMN1; SMN2KDM4E | |
| SCHEMBL1621632 | 0.77 | CNR2 (0.53) | TRPV1CNR2CNR1LMNA | |
| SCHEMBL1621889 | 0.77 | CNR2 (0.53) | CNR2CNR1MAPTEPHX2LMNA | |
| SCHEMBL1621259 | 0.77 | CNR2 (0.53) | CNR2CNR1KDM4E | |
| SCHEMBL1620082 | 0.76 | CNR2 (0.52) | CNR2CNR1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL15219082 | 0.75 | HSD17B10 (0.49) | TRPV1CNR2CNR1NPC1SMN1; SMN2 | |
| SCHEMBL1621040 | 0.74 | CNR2 (0.64) | TRPV1CNR2CNR1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074084-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-01 | — | — | EP | claimed |
| WO-2008039645-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-04-03 | — | — | WO | claimed |