Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 4/20 | 0.48 |
| ▸ | CNR1 | P21554 | 3/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1619672 | 0.80 | CNR2 (0.56) | HSD17B10KDM4ENPC1SMN1; SMN2POLB | |
| SCHEMBL15219117 | 0.78 | RAB9A (0.47) | KDM4ENPC1SMN1; SMN2RAB9A | |
| SCHEMBL16358727 | 0.78 | KDM4E (0.46) | HSD17B10KDM4ENPC1SMN1; SMN2POLB | |
| SCHEMBL16358728 | 0.76 | CNR2 (0.45) | NPC1SMN1; SMN2RAB9ALMNACNR2 | |
| SCHEMBL4011979 | 0.75 | TRPV1 (0.52) | HSD17B10KDM4ENPC1SMN1; SMN2POLB | |
| SCHEMBL16358862 | 0.73 | RORC (0.44) | — | |
| SCHEMBL15219108 | 0.73 | RORC (0.44) | — | |
| SCHEMBL8115181 | 0.72 | TRPV1 (0.65) | HSD17B10KDM4ENPC1SMN1; SMN2POLB | |
| SCHEMBL15219079 | 0.72 | GCK (0.54) | KDM4ENPC1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL15219101 | 0.71 | CSF1R (0.34) | POLBCNR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074084-B1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2013-08-28 | — | — | EP | disclosed |