Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20919125 | 0.82 | CYP3A4 (0.59) | FFAR1CYP3A4CASP1RECQLDRD2 | |
| SCHEMBL4968126 | 0.80 | CYP3A4 (0.58) | FFAR1CYP3A4CASP1RECQLPIK3CA | |
| SCHEMBL13529220 | 0.80 | FFAR1 (0.47) | FFAR1CYP3A4CASP1RECQLDRD2 | |
| SCHEMBL2810465 | 0.80 | FFAR1 (0.44) | FFAR1CYP3A4CASP1RECQLDRD2 | |
| SCHEMBL7402987 | 0.80 | FFAR1 (0.44) | FFAR1CYP3A4CASP1RECQLDRD2 | |
| Hydrochloric Acid SCHEMBL25281417 | 0.80 | BLM (0.61) | FFAR1CYP3A4CASP1RECQLDRD2 | |
| SCHEMBL23426194 | 0.77 | CYP2D6 (0.47) | FFAR1CYP3A4CASP1RECQLDRD2 | |
| SCHEMBL5425213 | 0.77 | ASIC3 (0.62) | FFAR1CYP3A4CASP1RECQLDRD2 | |
| SCHEMBL9611202 | 0.76 | FFAR1 (0.59) | FFAR1CYP3A4CASP1RECQLPIK3CA | |
| SCHEMBL2266577 | 0.76 | CYP3A4 (0.52) | FFAR1CYP3A4CASP1RECQLDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080722-A2 | CARBOXYLIC DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2009-07-02 | — | — | WO | disclosed |