Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.54 |
| ▸ | RELA | Q04206 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 5/20 | 0.53 |
| ▸ | GPER1 | Q99527 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13768431 | 0.92 | KMT2A (0.54) | KMT2AMEN1LMNAKDM4ENPC1 | |
| SCHEMBL4010576 | 0.92 | MEN1 (0.58) | KMT2AMEN1LMNAKDM4ENPC1 | |
| SCHEMBL13768327 | 0.90 | NPC1 (0.57) | KMT2AMEN1LMNAKDM4ENPC1 | |
| SCHEMBL4015480 | 0.86 | ABL1 (0.60) | KMT2AMEN1LMNAKDM4ENPC1 | |
| SCHEMBL4010897 | 0.86 | MEN1 (0.58) | KMT2AMEN1LMNAKDM4ENPC1 | |
| SCHEMBL4015936 | 0.86 | LMNA (0.54) | KMT2AMEN1LMNAKDM4ENPC1 | |
| SCHEMBL4010803 | 0.83 | MEN1 (0.54) | KMT2AMEN1LMNAKDM4ENPC1 | |
| SCHEMBL4009468 | 0.82 | SCD (0.53) | KMT2AMEN1LMNAKDM4ENPC1 | |
| SCHEMBL4010872 | 0.81 | ABL1 (0.56) | KMT2AMEN1LMNAKDM4ENPC1 | |
| SCHEMBL4010428 | 0.81 | ABL1 (0.56) | KMT2AMEN1LMNAKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009085256-A1 | ANTI-HIV COMPOUNDS | PANACOS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |