Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | XIAP | P98170 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4017230 | 0.88 | CNR2 (0.35) | LMNANPC1SMN1; SMN2GAA | |
| SCHEMBL4018062 | 0.83 | CNR2 (0.33) | GAA | |
| SCHEMBL1620953 | 0.81 | KMT2A (0.46) | LMNANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1621078 | 0.68 | CNR2 (0.49) | LMNANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1621933 | 0.67 | KMT2A (0.49) | LMNANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1621935 | 0.67 | KMT2A (0.43) | LMNANPC1RAB9AALDH1A1GAA | |
| SCHEMBL3963148 | 0.66 | CNR2 (0.44) | LMNAALDH1A1GAA | |
| SCHEMBL1621823 | 0.66 | ITGB1 (0.43) | LMNASMN1; SMN2ITGB1ITGA4 | |
| SCHEMBL3654247 | 0.66 | KMT2A (0.42) | LMNANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1464185 | 0.65 | LMNA (0.54) | LMNANPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074084-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-01 | — | — | EP | claimed |
| WO-2008039645-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-04-03 | — | — | WO | claimed |