Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3943471 | 1.00 | MCOLN3 (0.49) | MCOLN3L3MBTL1POLBALDH1A1KMT2A | |
| SCHEMBL9865528 | 0.87 | MCOLN3 (0.50) | MCOLN3L3MBTL1POLBALDH1A1KMT2A | |
| SCHEMBL2389473 | 0.87 | MCOLN3 (0.50) | MCOLN3L3MBTL1POLBALDH1A1KMT2A | |
| SCHEMBL9211270 | 0.87 | MCOLN3 (0.50) | MCOLN3L3MBTL1POLBALDH1A1KMT2A | |
| SCHEMBL9380136 | 0.87 | MCOLN3 (0.50) | MCOLN3L3MBTL1POLBALDH1A1KMT2A | |
| SCHEMBL2389980 | 0.87 | MCOLN3 (0.50) | MCOLN3L3MBTL1POLBALDH1A1KMT2A | |
| SCHEMBL9684628 | 0.87 | MCOLN3 (0.50) | MCOLN3L3MBTL1POLBALDH1A1KMT2A | |
| SCHEMBL9685672 | 0.87 | MCOLN3 (0.50) | MCOLN3L3MBTL1POLBALDH1A1KMT2A | |
| SCHEMBL8474798 | 0.85 | POLB (0.50) | MCOLN3L3MBTL1POLBALDH1A1KMT2A | |
| SCHEMBL3934944 | 0.81 | ALDH1A1 (0.44) | MCOLN3L3MBTL1ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106599-A2 | SUBSTITUTED PIPERIDINES AS THERAPEUTIC COMPOUNDS | NOVARTIS AG (CH) | 2009-09-03 | — | — | WO | disclosed |
| EP-2044059-A1 | 2,5-DISUBSTITUTED PIPERIDINES | Speedel Experimenta AG (CH) | 2009-04-08 | — | — | EP | disclosed |
| WO-2007141318-A1 | 2,5-DISUBSTITUTED PIPERIDINES | SPEEDEL EXPERIMENTA AG (CH) | 2007-12-13 | — | — | WO | disclosed |