Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 20/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL876086 | 0.85 | PTPRB (0.45) | PTPRB | |
| SCHEMBL19649501 | 0.80 | PTPRB (0.45) | PTPRB | |
| SCHEMBL19649500 | 0.72 | PTPRB (0.51) | PTPRB | |
| SCHEMBL14635271 | 0.70 | PTPRB (0.74) | PTPRB | |
| SCHEMBL14635272 | 0.70 | PTPRB (0.74) | PTPRB | |
| SCHEMBL19575794 | 0.68 | PTPRB (0.56) | PTPRB | |
| SCHEMBL16573545 | 0.67 | PTPRB (0.64) | PTPRBPTPN11 | |
| SCHEMBL22627135 | 0.67 | PTPRB (0.64) | PTPRBPTPN11 | |
| SCHEMBL19649516 | 0.66 | PTPRB (0.68) | PTPRB | |
| SCHEMBL21308071 | 0.65 | PTPRB (0.63) | PTPRBPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041102-A2 | HUMAN PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE | The Procter & Gamble Company (US) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008002569-A2 | HUMAN PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE | THE PROCTER & GAMBLE COMPANY (US) | 2008-01-03 | — | — | WO | disclosed |