Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 18/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL876086 | 0.83 | PTPRB (0.45) | PTPRB | |
| SCHEMBL21514754 | 0.80 | RAD52 (0.36) | TAAR1RAD52 | |
| SCHEMBL4012767 | 0.80 | PTPRB (0.43) | PTPRB | |
| SCHEMBL5112414 | 0.79 | TAAR1 (0.44) | TAAR1RAD52 | |
| SCHEMBL19575794 | 0.74 | PTPRB (0.56) | PTPRB | |
| SCHEMBL19649500 | 0.74 | PTPRB (0.51) | PTPRB | |
| SCHEMBL19649516 | 0.74 | PTPRB (0.68) | PTPRBTAAR1 | |
| SCHEMBL11757925 | 0.74 | PTPRB (0.56) | PTPRB | |
| SCHEMBL14635271 | 0.71 | PTPRB (0.74) | PTPRB | |
| SCHEMBL14635272 | 0.71 | PTPRB (0.74) | PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2803663-B1 | Human protein tyrosine phosphatase inhibitors and their pharmaceutical use | AERPIO THERAPEUTICS INC (US) | 2017-11-29 | — | — | EP | disclosed |