Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23153621 | 0.90 | ATR (1.00) | ATR | |
| SCHEMBL23153629 | 0.89 | ATR (0.93) | ATR | |
| SCHEMBL23153623 | 0.86 | ATR (0.77) | ATR | |
| SCHEMBL23153614 | 0.86 | ATR (1.00) | ATR | |
| SCHEMBL13138778 | 0.81 | ATR (0.78) | ATR | |
| SCHEMBL13138782 | 0.81 | ATR (0.77) | ATR | |
| SCHEMBL4439513 | 0.81 | ATR (0.81) | ATR | |
| SCHEMBL3063607 | 0.81 | ATR (1.00) | ATR | |
| SCHEMBL29458584 | 0.81 | ATR (1.00) | ATR | |
| SCHEMBL4045227 | 0.80 | ATR (0.68) | ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007390-A2 | 2-PYRAZ INYLBENZ IMIDAZOLE DERIVATIVES AS RECEPTOR TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2009-01-15 | — | — | WO | claimed |