Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4439513 | 0.91 | ATR (0.81) | ATREGFR | |
| SCHEMBL13942955 | 0.84 | EGFR (0.58) | ATREGFR | |
| SCHEMBL4044896 | 0.83 | ATR (0.68) | ATR | |
| SCHEMBL29458584 | 0.81 | ATR (1.00) | ATR | |
| SCHEMBL3063607 | 0.81 | ATR (1.00) | ATR | |
| SCHEMBL2509386 | 0.80 | ATR (1.00) | ATR | |
| SCHEMBL4012884 | 0.80 | ATR (0.81) | ATR | |
| SCHEMBL23153629 | 0.79 | ATR (0.93) | ATR | |
| SCHEMBL4003249 | 0.78 | ATR (0.64) | ATREGFR | |
| SCHEMBL2509492 | 0.77 | ATR (1.00) | ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009024825-A1 | 2-PYRAZINYLBENZIMIDAZOLE DERIVATIVES AS RECEPTOR TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2009-02-26 | — | — | WO | disclosed |