Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.68 |
| ▸ | ALPL | P05186 | 2/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | FABP1 | P07148 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3934462 | 0.89 | FAAH (0.72) | FAAHALPLEPHX2ALDH1A1LMNA | |
| SCHEMBL3939171 | 0.89 | FAAH (0.77) | FAAHALPLEPHX2ALDH1A1LMNA | |
| SCHEMBL4017265 | 0.88 | FAAH (0.82) | FAAHALPLALDH1A1LMNAMAPK1 | |
| SCHEMBL3943262 | 0.88 | FAAH (0.76) | FAAHALPLEPHX2ALDH1A1LMNA | |
| SCHEMBL3936957 | 0.87 | FAAH (0.75) | FAAHALPLEPHX2ALDH1A1LMNA | |
| SCHEMBL4018424 | 0.87 | FAAH (0.75) | FAAHEPHX2ALDH1A1LMNAMAPK1 | |
| SCHEMBL4016363 | 0.86 | FAAH (0.79) | FAAHALPLALDH1A1LMNAMAPK1 | |
| SCHEMBL3931640 | 0.85 | FAAH (0.73) | FAAHALPLEPHX2ALDH1A1LMNA | |
| SCHEMBL3930939 | 0.85 | FAAH (0.73) | FAAHALPLALDH1A1LMNAMAPK1 | |
| SCHEMBL3936249 | 0.84 | FAAH (0.72) | FAAHALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |