Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 10/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4015965 | 0.97 | RPA1 (0.41) | RPA1NOTUMCNR1CNR2GAA | |
| SCHEMBL4013777 | 0.86 | RPA1 (0.47) | RPA1NOTUMGAAL3MBTL1KDM4E | |
| SCHEMBL13901603 | 0.79 | KMT2A (0.55) | NOTUML3MBTL1HTT | |
| SCHEMBL13901607 | 0.78 | CYP2C19 (0.41) | RPA1CNR1CNR2L3MBTL1KDM4E | |
| SCHEMBL13901636 | 0.76 | POLB (0.50) | CNR1CNR2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL4015298 | 0.75 | CNR1 (0.43) | CNR1CNR2KDM4EALDH1A1 | |
| SCHEMBL13901639 | 0.74 | TP53 (0.49) | RPA1CNR1CNR2GAAKDM4E | |
| SCHEMBL13901649 | 0.73 | TP53 (0.45) | CNR1CNR2GAAKDM4EALDH1A1 | |
| SCHEMBL4019680 | 0.73 | ALDH1A1 (0.38) | RPA1NOTUMCNR1CNR2KDM4E | |
| SCHEMBL4012704 | 0.73 | RPA1 (0.43) | RPA1CNR1CNR2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011850-A2 | NOVEL THERAPEUTIC COMPOUNDS | ABBOTT LABORATORIES (US) | 2009-01-22 | — | — | WO | disclosed |