Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15913328 | 0.85 | GRIK1 (0.33) | GRIK1GRIK2NPSR1ALDH1A1 | |
| SCHEMBL15913809 | 0.83 | NPSR1 (0.36) | GRIK1GRIK2NPSR1EPHX1MAPT | |
| SCHEMBL4014181 | 0.80 | RECQL (0.34) | — | |
| SCHEMBL4769947 | 0.79 | CES2 (0.39) | GRIK1NPSR1SMN1; SMN2 | |
| SCHEMBL4769941 | 0.79 | CES2 (0.39) | GRIK1NPSR1SMN1; SMN2 | |
| SCHEMBL10471561 | 0.79 | NPSR1 (0.33) | GRIK1GRIK2NPSR1EPHX1ALDH1A1 | |
| SCHEMBL10471560 | 0.79 | NPSR1 (0.33) | GRIK1GRIK2NPSR1EPHX1ALDH1A1 | |
| SCHEMBL29117806 | 0.77 | GRIK1 (0.41) | GRIK1GRIK2NPSR1EPHX1ALDH1A1 | |
| SCHEMBL12639567 | 0.77 | GRIK1 (0.41) | GRIK1GRIK2NPSR1EPHX1ALDH1A1 | |
| SCHEMBL27549573 | 0.77 | GRIK1 (0.41) | GRIK1GRIK2NPSR1EPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |