Sugi Predict

Sugi Predict / Compounds / SCHEMBL4014271

SCHEMBL4014271

SCHEMBL4014271

CCCC[C@@H](C)C[C@@H](CC(=O)O)NC(=O)[C@@H](N)C(C)C

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ DPP7 Q9UHL4 7/20 0.52
▸ DPP8 Q6V1X1 6/20 0.52
▸ DPP4 P27487 5/20 0.52
▸ DPP9 Q86TI2 5/20 0.52
▸ PLA2G10 O15496 3/20 0.40
▸ PDF Q9HBH1 1/20 0.39
▸ SLC15A1 P46059 1/20 0.38
▸ FAP Q12884 1/20 0.37
▸ MMP2 P08253 5/20 0.36
▸ MMP3 P08254 5/20 0.36
▸ MMP1 P03956 3/20 0.36
▸ MMP7 P09237 1/20 0.36
▸ SLC1A3 P43003 1/20 0.36
▸ SLC1A2 P43004 1/20 0.36
▸ SLC1A1 P43005 1/20 0.36
▸ PLA2G2C Q5R387 1/20 0.35
▸ GPR84 Q9NQS5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4009822 1.00 DPP7 (0.52) DPP7DPP8DPP4DPP9PLA2G10
SCHEMBL4008835 1.00 DPP7 (0.52) DPP7DPP8DPP4DPP9PLA2G10
SCHEMBL4008004 1.00 DPP7 (0.52) DPP7DPP8DPP4DPP9PLA2G10
SCHEMBL4016345 0.92 DPP8 (0.44) DPP7DPP8DPP4DPP9PLA2G10
SCHEMBL4014220 0.92 DPP8 (0.44) DPP7DPP8DPP4DPP9PLA2G10
SCHEMBL4008854 0.92 DPP8 (0.44) DPP7DPP8DPP4DPP9PLA2G10
SCHEMBL4010009 0.92 DPP8 (0.44) DPP7DPP8DPP4DPP9PLA2G10
SCHEMBL4008905 0.89 DPP8 (0.41) DPP7DPP8DPP4DPP9PLA2G10
SCHEMBL4009478 0.89 DPP8 (0.41) DPP7DPP8DPP4DPP9PLA2G10
SCHEMBL4007774 0.89 DPP8 (0.41) DPP7DPP8DPP4DPP9PLA2G10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7491835-B2 Prodrugs of amino acids with affinity for the α2δ-protein PFIZER INC (US) 2009-02-17 — — US claimed
EP-1670750-A1 PRODRUGS OF AMINO ACIDS WITH AFFINITY FOR THE ALPHA2DELTA- PROTEIN Warner-Lambert Company LLC (US) 2006-06-21 — — EP claimed
WO-2005030703-A1 PRODRUGS OF AMINO ACIDS WITH AFFINITY FOR THE α2δ- PROTEIN WARNER-LAMBERT COMPANY LLC (US) 2005-04-07 — — WO claimed
US-20050070483-A1 Prodrugs of amino acids with affinity for the alpha2delta-protein VIATRIS SPECIALTY LLC. 2005-03-31 — — US claimed
US-7491835-B2 Prodrugs of amino acids with affinity for the α2δ-protein PFIZER INC (US) 2009-02-17 — — US disclosed
EP-1670750-A1 PRODRUGS OF AMINO ACIDS WITH AFFINITY FOR THE ALPHA2DELTA- PROTEIN Warner-Lambert Company LLC (US) 2006-06-21 — — EP disclosed
WO-2005030703-A1 PRODRUGS OF AMINO ACIDS WITH AFFINITY FOR THE α2δ- PROTEIN WARNER-LAMBERT COMPANY LLC (US) 2005-04-07 — — WO disclosed
US-20050070483-A1 Prodrugs of amino acids with affinity for the alpha2delta-protein VIATRIS SPECIALTY LLC. 2005-03-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050070483-A1 Prodrugs of amino acids with affinity for the alpha2delta-protein SCN2A, OPRD1, SCN1A DPP7 1105/4885DPP8 2187/4885DPP4 1906/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.