Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 10/20 | 0.50 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4414424 | 0.80 | TNF (0.56) | TNF | |
| SCHEMBL3401964 | 0.80 | TNF (0.45) | TNFCREBBPMEN1KMT2ATUBB4A | |
| SCHEMBL6754124 | 0.75 | TNF (0.45) | TNFCREBBPTUBB4ATUBBTUBA3C | |
| SCHEMBL2123060 | 0.72 | MGAM (0.46) | TNFCREBBPTUBB4ATUBBTUBA3C | |
| SCHEMBL7430918 | 0.71 | TNF (0.51) | TNFCREBBPMEN1KMT2AKAT2B | |
| SCHEMBL16363382 | 0.69 | FGFR1 (0.43) | KAT2BMTNR1AMTNR1BKDM4EALDH1A1 | |
| SCHEMBL24476442 | 0.68 | HDAC1 (0.43) | TNFKAT2BMTNR1AMTNR1BMAPT | |
| SCHEMBL18463253 | 0.68 | CYP1A2 (0.42) | TNFHSP90AA1HPGD | |
| SCHEMBL2747904 | 0.68 | TNF (0.42) | TNFCREBBPMEN1KMT2AKAT2B | |
| SCHEMBL2123687 | 0.67 | TNF (0.42) | TNFCREBBPKMT2ATUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014659-A1 | New hybrid compounds of nucleobases and organic redox molecules and their use | Universität Osnabrück (DE) | 2009-01-14 | — | — | EP | disclosed |