Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 10/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 2/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2123060 | 0.85 | MGAM (0.46) | TNFCREBBPFPR2TUBB4ATUBB | |
| SCHEMBL3401964 | 0.82 | TNF (0.45) | TNFCREBBPFPR2FGFR1FGFR4 | |
| SCHEMBL2616391 | 0.82 | TNF (0.42) | TNFCREBBPFPR2TUBB4ATUBB | |
| SCHEMBL2123687 | 0.82 | TNF (0.42) | TNFCREBBPFPR2TUBB4ATUBB | |
| SCHEMBL2125588 | 0.80 | FPR2 (0.41) | TNFCREBBPFPR2TUBB4ATUBB | |
| SCHEMBL2616390 | 0.79 | TNF (0.40) | TNFCREBBPFPR2TUBB4ATUBB | |
| SCHEMBL2616387 | 0.79 | TNF (0.40) | TNFCREBBPFPR2TUBB4ATUBB | |
| SCHEMBL2123430 | 0.78 | TNF (0.50) | TNF | |
| SCHEMBL2122939 | 0.78 | TNF (0.41) | TNFCREBBPFPR2TUBB4ATUBB | |
| SCHEMBL23885633 | 0.76 | LMNA (0.45) | FGFR1FGFR4LMNAPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040209929-A1 | Fused heteroaryl carboxylic acids as PPAR agonists | AGOURON PHARMACEUTICALS, INC. | 2004-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040209929-A1 | Fused heteroaryl carboxylic acids as PPAR agonists | PPARG, PPARA, PPARD | TNF 1388/4885CREBBP 879/4885FPR2 576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.