Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 18/20 | 0.77 |
| ▸ | SLC6A4 | P31645 | 18/20 | 0.77 |
| ▸ | HTR1A | P08908 | 17/20 | 0.77 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.77 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4006996 | 0.99 | SLC6A2 (0.75) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C | |
| Hydrochloric Acid SCHEMBL4007582 | 0.86 | HTR1A (0.97) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C | |
| SCHEMBL13770273 | 0.85 | HTR1A (0.80) | SLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL13769617 | 0.83 | HTR1A (1.00) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C | |
| SCHEMBL13769759 | 0.83 | HTR1A (1.00) | SLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL13769615 | 0.82 | SLC6A2 (0.74) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C | |
| Hydrochloric Acid SCHEMBL4013707 | 0.82 | HTR1A (0.97) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C | |
| Hydrochloric Acid SCHEMBL4007273 | 0.82 | HTR1A (0.97) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C | |
| SCHEMBL5669748 | 0.82 | SLC6A2 (0.68) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C | |
| Hydrochloric Acid SCHEMBL4010932 | 0.81 | SLC6A2 (0.73) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081259-A1 | PHENOXY-PYRIDYL DERIVATIVES | PFIZER INC. (US) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009081259-A1 | PHENOXY-PYRIDYL DERIVATIVES | PFIZER INC. (US) | 2009-07-02 | — | — | WO | disclosed |