Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4007168 | 0.91 | PTGDR2 (0.43) | PTGDR2KMT2ATP53HCRTR1HCRTR2 | |
| SCHEMBL1864812 | 0.87 | PTGER1 (0.37) | PTGDR2KMT2ATP53HCRTR1HCRTR2 | |
| SCHEMBL4014559 | 0.84 | LMNA (0.41) | PTGDR2KMT2AALDH1A1MAPK1LMNA | |
| SCHEMBL1856515 | 0.80 | MAPT (0.44) | KMT2ATP53HCRTR1HCRTR2MAPT | |
| SCHEMBL1860465 | 0.78 | PTGDR2 (0.38) | PTGDR2KMT2ATP53HCRTR1HCRTR2 | |
| SCHEMBL4011688 | 0.77 | PTGDR2 (0.43) | PTGDR2KMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL3466973 | 0.75 | CA12 (0.42) | PTGDR2KMT2ATP53HCRTR2MAPT | |
| SCHEMBL1857094 | 0.74 | F2 (0.40) | PTGDR2KMT2ALMNAHTTCA12 | |
| SCHEMBL4008265 | 0.74 | LMNA (0.41) | PTGDR2KMT2AALDH1A1MAPK1LMNA | |
| SCHEMBL6799209 | 0.73 | MAPT (0.52) | KMT2ATP53MAPTTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080722-A2 | CARBOXYLIC DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2009-07-02 | — | — | WO | disclosed |