Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.80 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.80 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL2466156 | 1.00 | CA5A (0.80) | CA5ACA5BMEN1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL10339100 | 1.00 | — | — | |
| Nitric Acid SCHEMBL218219 | 1.00 | — | — | |
| Nitric Acid SCHEMBL7126708 | 1.00 | — | — | |
| Nitric Acid SCHEMBL94578 | 1.00 | CA5A (0.80) | CA5ACA5BMEN1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL9162752 | 1.00 | — | — | |
| Nitric Acid SCHEMBL7125664 | 1.00 | CA5A (0.80) | CA5ACA5BMEN1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL407617 | 1.00 | CA5A (0.80) | CA5ACA5BMEN1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL8982116 | 0.95 | — | — | |
| Nitric Acid SCHEMBL8982097 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534415-B2 | Mesostructured transition aluminas | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2009-05-19 | — | — | US | disclosed |
| US-20070152181-A1 | Mesostructured hydrated alumina - surfactant composite compositions and mesostructured transition alumina compositions derived therefrom | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2007-07-05 | — | — | US | disclosed |
| US-7090824-B2 | Mesostructured transition aluminas | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2006-08-15 | — | — | US | disclosed |
| US-20060120952-A1 | Mesostructured transition aluminas | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2006-06-08 | — | — | US | disclosed |
| US-20030052047-A1 | Mesostructured transition aluminas | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 2003-03-20 | — | — | US | disclosed |
| WO-2003011759-A1 | MESOSTRUCTURED TRANSITION ALUMINAS | MICHIGAN STATE UNIVERSITY (US) | 2003-02-13 | — | — | WO | disclosed |