Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HRH2 | P25021 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26620224 | 0.97 | TLR7 (0.53) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL31379717 | 0.94 | TLR7 (0.53) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL144931 | 0.94 | TLR7 (0.53) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL5139195 | 0.93 | TLR7 (0.44) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL148087 | 0.92 | TLR7 (0.57) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL4621585 | 0.89 | TLR7 (0.41) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL144157 | 0.89 | TLR7 (0.58) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL31092872 | 0.88 | TLR7 (0.51) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL147063 | 0.88 | TLR7 (0.51) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL4555124 | 0.88 | TLR7 (0.48) | TLR7TLR8LMNAPOLBHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2043683-A2 | FROZEN STOCKPILING OF INFLUENZA VACCINES | Novartis AG (CH) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008017956-A2 | FROZEN STOCKPILING OF INFLUENZA VACCINES | NOVARTIS AG (CH) | 2008-02-14 | — | — | WO | disclosed |