Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3275133 | 0.97 | TLR7 (0.41) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL4556287 | 0.93 | TLR7 (0.42) | TLR7TLR8 | |
| SCHEMBL25338771 | 0.93 | TLR7 (0.42) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL4238527 | 0.93 | TLR7 (0.45) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL19347607 | 0.91 | TLR7 (0.43) | TLR7TLR8 | |
| SCHEMBL5139195 | 0.90 | TLR7 (0.44) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL4015090 | 0.89 | TLR7 (0.50) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL4019917 | 0.87 | TLR7 (0.50) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL26620224 | 0.87 | TLR7 (0.53) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL4555124 | 0.85 | TLR7 (0.48) | TLR7TLR8LMNAPOLBHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945253-A2 | ADMINSTRATION ROUTES FOR PRIMING/BOOSTING WITH INFLUENZA VACCINES | Novartis Vaccines and Diagnostics S.r.l. (IT) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007052057-A2 | ADMINSTRATION ROUTES FOR PRIMING/BOOSTING WITH INFLUENZA VACCINES | NOVARTIS VACCINES AND DIAGNOSTICS SRL (IT) | 2007-05-10 | — | — | WO | disclosed |